Female alopecia: causes and treatments

Our medical advisor Clara Serés tells us the main causes of female alopecia and the possible treatments to combat it. In our next post we will share a success story. Female alopecia To understand female alopecia, we must take into account the physiological process of hair growth without forgetting genetic, hormonal, metabolic aspects, deficiencies of vitamins, minerals and / or trace elements, the influence of chronic and / or acute stress, in addition to anemic states of ferropenic type. The replacement of the different hair follicles of each hair root throughout life and the hair renewal system with its 3 stages also involves seasonal hair loss (telogen effluvium). They are harmless in general, respond to the normal evolutionary process of hair growth and are fully reversible. The most common forms of alopecia in women are telogen effluvium and androgenic alopecia. The proper diagnosis of the type of alopecia that the patient presents determines the treatment and prognosis.

In the case of telogen effluvium,patients perceive an increase in hair loss after washing their hair, on the pillow, etc. It is a reversible process that can be caused by different causes such as pregnancy, stress, diets, etc.

In the case of androgenic alopecia it is necessary to perform an active treatment to stop hair loss, because if it is not progressively losing density at the level of the scalp.

Pharmacological treatments The management of androgenic alopecia (also called androgenetics, because of its genetic component) is mainly pharmacological. We differentiate a topical treatment (minoxidil 2% or 5%) and a systemic treatment (antiandrogen drugs: finasteride and dutasteride).

Topical treatment is used in both males and females.

The systemic, with finasteride and dutasteride (greater action), is used to a greater extent in men, although there are studies that demonstrate its effectiveness in postmenopausal women. They are long-lasting treatments although they do not have to be for life.

Antiandrogen drugs can also be used locally, by infiltrating the scalp after applying local anesthesia. This procedure can be used every 4-6 months as an adjunct or even as an isolated treatment in some patients. In women, treatment is based on minoxidil and another antiandrogen profile, such as flutamide at low doses. It is essential to identify if there is any underlying hormonal alteration such as polycystic ovary syndrome,and in cases like that, based on an endocrinological study, assess the use of hormonal contraceptives. Non-pharmacological treatments As a non-pharmacological treatment, we have several options:

Biostimulation of platelet-rich plasma (PRP) with growth factors. It consists of extracting blood from the patient himself and isolating the portion of platelet-rich plasma with growth factors that infiltrates the areas of the scalp to be treated.

Stimulates follicular growth.

Increases the diameter of the hair.

There are usually 3-4 sessions a year.

It is usually used as an adjunct to medical treatment with minoxidil or antiandrogens.

Treatments from sterile formulations of pharmaceutical production with specific substances. Mesoceuticals® are an alternative and/or complement to the therapies described above. Both pharmacological and non-pharmacological.

High concentrations of active ingredients inhibit, among other actions, the action of 5 alpha reductase (enzyme that allows the passage of testosterone to DiHydroTestosterone -DHT-).

Cocktails that unite substances with synergistic action.

Other formulations that include new generation peptides in a higher percentage and that allow an intra and intercellular messaging action that regulates and modulates the diminished processes of hair growth.

Treatment of female alopecia with Mesoceuticals® One aspect to take into account in the local application of Mesoceuticals® in female patients is the location of the treatment areas. In women, the most common area that is depopulated with hair is the central area of the line that expands, starting baldness just after the frontal area. In man, on the other hand, the areas most commonly affected are the "entrances", and the area of the crown Thus, the Mesoceuticals® will be applied properly and in the appropriate place as the case may be; following the patterns of each gender, male or female. If we take as an example a patient with incipient androgenic alopecia of 4 years of evolution, who accuses areas with low density of hair in typically characteristic areas as described above, the first thing is to make an adequate diagnosis. A dermatologist and, if possible, trichologist, will indicate to the patient the necessary tests to confirm or identify the type of alopecia, ruling out deficiencies that could cause or aggravate the patient's hair loss. In addition to an analytical and correct anamnesis, if the specialist considers it appropriate, he will do more tests that allow to visualize the miniaturization of the hair due to the effect of the androgen hormonal imbalance that affects the hair follicle. If the case is considered with the severity or evolution to indicate an oral pharmacological therapy, this can also be combined and completed by the use of Mesoceuticals®. Its application will be scheduled in several sessions that can go from 5 to 10 and that, over time, can be repeated at key moments (before the seasonal times in which the hair goes through a replacement that manifests itself with greater fall). In certain cases in which by genetic inheritance you want to do preventive therapy, this option is an excellent choice. In addition, of the Mesoceuticals themselves® specific for alopecia, there are others that can be combined to maintain an adequate state of the scalp and optimize aspects of blood supply and optimal nutritional contribution for the follicles.

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